Ultrastructural study of spontaneous bone marrow rosette-forming cells
| Autor: | B Nabarra, J F Bach, J F Cavellier, J Charreire |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Cell
Golgi Apparatus Bone Marrow Cells Mitochondrion Biology Rosette (botany) Mice Bone Marrow medicine Animals Lymphocytes Cell Nucleus Macrophages Cell Biology Articles Molecular biology Mitochondria Mice Inbred C57BL Cell nucleus medicine.anatomical_structure Immunology Myeloid-derived Suppressor Cell Ultrastructure Immunologic Techniques Bone marrow Ribosomes Hormone |
| Zdroj: | The Journal of Cell Biology |
| ISSN: | 0021-9525 |
| Popis: | Mouse bone marrow contains spontaneous rosette-forming cells (RFC) which include more than 70% T-cell precursors, as assessed by their transformation into theta-positive cells after incubation with thymic hormone. Such spontaneous RFC, examined in C57B1/6 mouse bone marrow by electron and scanning electron microscopy, have consistently been shown to be small, inactive mouse lymphocytes when macrophages have been eliminated by cell preincubation. These data suggest that thymic hormone target cells include small quiescent lymphocytes. |
| Databáze: | OpenAIRE |
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