| Autor: |
L, Cattin, F, Ferrari, S, Mongodi, E, Pariani, G, Bettini, F, Daverio, K, Donadello, E, Polati, F, Mojoli, V, Danzi, S, De Rosa |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Popis: |
Few studies have reported the implications and adverse events of performing endotracheal intubation for critically ill COVID-19 patients admitted to intensive care units. The aim of the present study was to determine the adverse events related to tracheal intubation in COVID-19 patients, defined as the onset of hemodynamic instability, severe hypoxemia, and cardiac arrest.Tertiary care medical hospitals, dual-centre study performed in Northern Italy from November 2020 to May 2021.Adult patients with positive SARS-CoV-2 PCR test, admitted for respiratory failure and need of advanced invasive airways management.Endotracheal Intubation Adverse Events.The primary endpoint was to determine the occurrence of at least 1 of the following events within 30 minutes from the start of the intubation procedure and to describe the types of major adverse peri-intubation events: severe hypoxemia defined as an oxygen saturation as measured by pulse-oximetry80%; hemodynamic instability defined as a SBP 65 mmHg recoded at least once or SBP 90 mmHg for 30 minutes, a new requirement or increase of vasopressors, fluid bolus15 mL/kg to maintain the target blood pressure; cardiac arrest.Among 142 patients, 73.94% experienced at least one major adverse peri-intubation event. The predominant event was cardiovascular instability, observed in 65.49% of all patients undergoing emergency intubation, followed by severe hypoxemia (43.54%). 2.82% of the patients had a cardiac arrest.In this study of intubation practices in critically ill patients with COVID-19, major adverse peri-intubation events were frequent.www.gov identifier: NCT04909476. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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