Quantification of smooth pursuit dysfunction in multiple sclerosis
| Autor: | Revere P. Kinkel, Miryam Palomino, Torge Rempe, Neda Dastgheyb, Jennifer Graves, Dorion Liston, Annalise E. Miner |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Multiple Sclerosis business.industry Multiple sclerosis General Medicine Audiology medicine.disease Smooth pursuit Pursuit Smooth 03 medical and health sciences Noise 0302 clinical medicine Neurology Healthy control medicine Saccades Eye tracking Humans 030212 general & internal medicine Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Multiple sclerosis and related disorders. 54 |
| ISSN: | 2211-0356 |
| Popis: | Background : Smooth pursuit dysfunction is common in MS, but rarely quantified and may be missed on exam. Methods : NeuroFitONE™ smooth pursuit performance measures were compared between MS (n = 20) and healthy control (n = 19) participants. Results : Compared to controls, MS patients had lower proportion of smooth pursuit (0.63 vs. 0.73; p = 0.047), increased directional (10.1 vs. 8°; p = 0.014) and speed noise (4.3 vs. 3.1°/sec; p = 0.021) and reduced initiation acceleration (96.83 vs. 115.33°/sec2; p = 0.061). Significant univariate correlations with clinical scores (EDSS, T25-FW) were observed. Conclusion : Smooth pursuit dysfunction in MS can be readily quantified and distinguishes MS eyes from healthy controls. |
| Databáze: | OpenAIRE |
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