Prophylactic negative pressure wound therapy after lower extremity fracture surgery: a pilot study

Autor: Vincent M. de Jong, Jan S. K. Luitse, J. Carel Goslings, Tim Schepers, Merel F. N. Birnie, Manouk Backes, Siem A. Dingemans
Přispěvatelé: AMS - Rehabilitation & Development, 02 Surgical specialisms, Graduate School, AMS - Amsterdam Movement Sciences, AMS - Restoration & Development, Surgery, Other Research, AMS - Musculoskeletal Health, Other departments, AMS - Sports
Rok vydání: 2018
Předmět:
Zdroj: International orthopaedics, 42(4), 747-753. Springer Verlag
ISSN: 1432-5195
0341-2695
DOI: 10.1007/s00264-018-3781-6
Popis: Infectious complications following lower extremity fracture surgery are a major concern and account for a substantial socio-economic burden to society. The aim of this pilot study was to investigate the feasibility of a new portable single-use negative pressure wound therapy device in patients undergoing major foot ankle surgery. Patients undergoing major foot ankle fracture surgery at a single level 1 trauma centre were eligible for this prospective case series. Patient characteristics were collected, as were fracture and surgical characteristics. Primary outcome was surgical site infection within 30 days as classified by the criteria from the Centers for Disease Control and Prevention. Patients in the prospective cohort were case-matched with a historical cohort from the same institution. Sixty patients were included. In seven patients, the NPWT failed and treatment was ceased. Mean age was 44 years and 85% was ASA 1; 43% of the patients were actively smoking. Indications for surgery were midfoot, calcaneal, talar, and ankle fractures. In 53 patients, four (7.5%) surgical site infections occurred, two superficial (3.3%) and two (3.3%) deep infections. For 47 patients, a match was available. The incidence of surgical site infection did not statistically significantly differ between the prospective cohort and retrospective matched cohort (4.3 versus 14.9%, p = 0.29, respectively). This was also the case when looking at superficial and deep surgical site infections separately (0 versus 8.5%, p = 0.08, and 4.3 versus 6.4%, respectively). We have observed surgical site infections in 7.5% of the patients with the use of prophylactic negative pressure wound therapy. The incidence of surgical site infections was not statistically significantly lower compared to a matched historical cohort.
Databáze: OpenAIRE
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