Medication with fenbendazole in feed: plasma concentrations and effects on hepatic xenobiotic metabolizing enzymes in swine

Autor:	Paula Ichinose, María Victoria Miró, Karen Larsen, Carlos Lanusse, Adrián Lifschitz, Guillermo Virkel
Rok vydání:	2022
Předmět:	General Veterinary General Medicine
Zdroj:	Veterinary research communications.
ISSN:	1573-7446
Popis:	Fenbendazole (FBZ), a benzymidazole (BZD) anthelmintic drug, is used for in-feed medication in pigs. BZD-containing drugs may induce cytochrome P450 isozymes (CYPs), particularly those members of the CYP1A subfamily. The current research evaluated the plasma and liver availability and metabolism of FBZ and its metabolites, oxfendazole (OFZ) and fenbendazole sulphone (FBZSO
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8027af877d8c7178bb3c231c099c7321 https://pubmed.ncbi.nlm.nih.gov/36542192 Zobrazit plný text záznamu Full text from SpringerLink