Effects of Temperature on the Ability of Metabolites from Permafrost Microorganisms to Activate the Synthesis of Systemic Cytokines by Mononuclear Cells
| Autor: | L. F. Kalenova, S. S. Kolyvanova |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Interleukin-1beta Bacillus cereus Permafrost Bacillus Peripheral blood mononuclear cell General Biochemistry Genetics and Molecular Biology Proinflammatory cytokine Microbiology 03 medical and health sciences 0302 clinical medicine Humans Secretion Cells Cultured Bacillus megaterium biology Strain (chemistry) Chemistry Tumor Necrosis Factor-alpha Temperature General Medicine biology.organism_classification Interleukin-10 030104 developmental biology Leukocytes Mononuclear Cytokines Tumor necrosis factor alpha 030217 neurology & neurosurgery Bacteria |
| Zdroj: | Bulletin of experimental biology and medicine. 168(1) |
| ISSN: | 1573-8221 |
| Popis: | The effects of metabolites of Bacillus sp. strain M3 and Bacillus megaterium strain 8/75-1 isolated from permafrost formations, as well as a medicinal Bacillus cereus strain IP5832 on the secretion of TNFα, IL-1β, and IL-10 by mononuclear cells of human peripheral blood depending on the temperature of bacteria culturing (-16oC, -5oC, and 42oC) were studied. Metabolites of 8/75-1 and M3 strains cultured at 42oC produced more potent stimulating effect on TNFα and IL-10 synthesis than metabolites from these bacteria cultured at -16oC and -5oC (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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