Profilassi antitromboembolica nel trauma scheletrico maggiore. Il punto di vista dell’ortopedico
| Autor: | Massimo Mariconda, Vincenzo Paolo Di Francia |
|---|---|
| Přispěvatelé: | Mariconda, Massimo, DI FRANCIA, VINCENZO PAOLO |
| Jazyk: | italština |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
medicine.drug_mechanism_of_action business.industry medicine.drug_class Deep vein Deep Vein Thrombosis pulmonary embolism skeletal trauma polytrauma thromboprophylaxis Factor Xa Inhibitor Low molecular weight heparin 030208 emergency & critical care medicine Heparin medicine.disease Polytrauma Thrombosis Surgery Pulmonary embolism 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Orthopedic surgery medicine 030212 general & internal medicine Intensive care medicine business medicine.drug |
| Popis: | Deep Vein Thrombosis (DVT) and pulmonary embolism ( $\mathit{PE}$ ) are important complications of major skeletal trauma and polytrauma that may occur after variable time following trauma and its treatment. A variety of risk factors including the complexity of fractures and associated injuries predispose these patient to DVT and PE. Hence, early and aggressive pharmacological prophylaxis must be carried out in this setting. Thromboprophylaxis needs to be balanced against the risk of haemorrhage. It could be useful to adopt a system to stratify the risk of thromboembolism in trauma patients and select the best option for an adequate prophylaxis. The available pharmacological agents include low-dose heparin, low molecular weight heparin, and factor Xa inhibitors. Mechanical prophylaxis methods include graduated compression stockings, pneumatic compression devices, and A-V foot pumps. Caval filters are an option in high-risk patients in whom pharmacological prophylaxis is contraindicated. All these prophylactic methods are reviewed. |
| Databáze: | OpenAIRE |
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