Role of chromogranin A-derived fragments after resection of nonfunctioning pancreatic neuroendocrine tumors

Autor: V. Andreasi, S. Partelli, M. F. Manzoni, F. Muffatti, L. Di Filippo, S. Crippa, A. Corti, M. Falconi
Přispěvatelé: Andreasi, V, Partelli, S, Manzoni, M F, Muffatti, F, Di Filippo, L, Crippa, S, Corti, A, Falconi, M
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Popis: No single reliable biomarker is available for nonfunctioning pancreatic neuroendocrine tumors (NF-PanNETs). Vasostatin-1 (VS-1), the N-terminal fragment of chromogranin A (CgA), seems to be a more accurate biomarker compared to its precursor. Primary aim was to investigate the ability of VS-1, compared to total-CgA, to assess the effectiveness of surgical resection performed for NF-PanNETs. Secondary aim was to evaluate two additional CgA-derived fragments, pancreastatin (PST) and vasostatin-2 (VS-2), as possible biomarkers for NF-PanNETs.
Databáze: OpenAIRE