IMMUNOLOGICAL STUDIES OF THE L-PHASE VARIANTS OF SOME E. COLI STRAINS
| Autor: | B. Kaijser, S. Seeberg, J.‐E. Brorson |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.disease_cause
Microbiology Antigen-Antibody Reactions Antigen Pseudomonas Escherichia coli Methods medicine Animals Escherichia coli Infections Antiserum Antigens Bacterial Bacteriological Techniques biology Immune Sera Penicillin G General Medicine Proteus biology.organism_classification Solid medium Culture Media Penicillin Antibody response Antibody Formation Urinary Tract Infections Rabbits Bacteria medicine.drug |
| Zdroj: | Acta Pathologica Microbiologica Scandinavica Section B Microbiology and Immunology. :777-787 |
| ISSN: | 0365-5563 |
| DOI: | 10.1111/j.0365-5563.1973.tb00001.x |
| Popis: | As a basis for the studies of the role of Escherichia coli L-phase variants in urinary tract infections the immunological characteristics of the L-phase variants of three E. coli strains were studied (E. coli O8:K8:H4; E. coli O2:K1:H4 and E. coli O15:K?:H?). The L-phase variants were induced by penicillin on solid media and could be subcultivated at least thirty times on penicillin-free media without reverting to bacteria. Antisera to the bacteria and L-phase variants were produced in rabbits. Most of the antigens in the bacteria were also found in the L-phase variants. All L-phase variants contained O antigen. In the L-phase variant of E. coli O8:K8:H4 K antigen was also found. In all the micro-organisms an antigen with high electrophoretic mobility common to many E. coli, Proteus and Pseudonomas strains was found. There was enough O antigen in all the L-phase variants to induce an O antibody response in rabbits similar to the O antibody response induced by complete bacteria. |
| Databáze: | OpenAIRE |
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