Impact of Anxiety or Depression Symptoms on Propofol Requirements for Sedation in Females: A Prospective Cohort Study
| Autor: | Ming Lin, Jian-Tong Shen, Shi-Hong Wen, Xu-Yu Zhang, Rui‐yun Li, Hong‐ye Jiang, Wenqi Huang |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Sedation Hysteroscopy Anxiety Hospital Anxiety and Depression Scale 030226 pharmacology & pharmacy 03 medical and health sciences 0302 clinical medicine Humans Hypnotics and Sedatives Medicine Pharmacology (medical) Prospective Studies Correlation of Data Infusions Intravenous Prospective cohort study Propofol Pharmacology Depression business.industry Perioperative Alertness Intravenous anesthesia 030220 oncology & carcinogenesis Anesthesia Female Deep Sedation medicine.symptom business medicine.drug |
| Zdroj: | The Journal of Clinical Pharmacology. 60:1376-1384 |
| ISSN: | 1552-4604 0091-2700 |
| DOI: | 10.1002/jcph.1631 |
| Popis: | Mental disorders are thought to affect various clinical outcomes during the perioperative period. Among them, anxiety and depression are 2 of the most common types. However, the impacts of anxiety or depression on propofol requirements remain unclear. This study aimed to investigate the effects of anxiety or depression symptoms on the propofol requirements for sedation in females. This study recruited female patients aged 18 to 65 years, with American Society of Anesthesiologists physical status classification of 1 to 2, who were scheduled for hysteroscopic surgery under propofol-based intravenous anesthesia. The day before surgery, the Hospital Anxiety and Depression Scale (HADS) was used to assess the symptoms of anxiety and depression within the past 6 months. Target-controlled propofol was gradually titrated to achieve 3 desired levels of sedation: Modified Observer's Assessment of Alertness/Sedation scale (MOAA/S) score 3, MOAA/S score 1, and MOAA/S score 1 and Narcotrend Index |
| Databáze: | OpenAIRE |
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