Primary stenting in acute myocardial infarction: a 30-day follow up study
| Autor: | Tapan Ghose, Dixit Ns, Upendra Kaul, Sudan D, Rakesh Sapra, Balbir Singh, Ram Dev Yadav |
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| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Myocardial Infarction Coronary Angiography Angioplasty Internal medicine medicine Humans Radiology Nuclear Medicine and imaging cardiovascular diseases Myocardial infarction Prospective Studies Ticlopidine Prospective cohort study Aged Aspirin Ejection fraction medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Coronary Vessels Treatment Outcome Regional Blood Flow Angiography Cardiology Female Stents Cardiology and Cardiovascular Medicine business TIMI medicine.drug Follow-Up Studies |
| Zdroj: | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventions. 46(1) |
| ISSN: | 1522-1946 |
| Popis: | Primary coronary stenting is being increasingly used in patients undergoing primary coronary angioplasty for acute myocardial infarction. In this prospective study we evaluated our experience of direct angioplasty in 68 patients with acute myocardial infarction of whom 57 received intracoronary stents using high-pressure deployment (> or =12 atmospheres) with adjunct aspirin and ticlopidine therapy without coumadin. All patients underwent pre-discharge follow-up angiography. Stent implantation was successful in all patients. Stent thrombosis was not seen in any patient. However, TIMI grade 3 flow was obtained in only 51 patients (89.6%) with evidence of slow flow present in remaining six patients. Follow-up angiograms showed no stent thrombosis but five out of the six patients (83%) with slow-flow phenomenon persisted to have slow flow. These patients had lower left ventricular ejection fraction as compared to patients with TIMI 3 flow at follow-up angiography (27.5 +/- 10.2% vs. 42.1 +/- 15.2%, P < .001) and a high mortality (two out of six) within 30 days. Primary stenting is safe and feasible in the majority of patients with good short-term outcomes, but persistent slow-flow phenomenon with adverse clinical outcome is seen in a small but significant number of patients. |
| Databáze: | OpenAIRE |
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