Improved long-term survival following pulmonary resections for non-small cell lung cancer: results of a nationwide study from Iceland

Autor: Astridur Petursdottir, Hannes Halldorsson, Bjorn Mar Fridriksson, Steinn Jonsson, Gudrun Nina Oskarsdottir, Tomas Gudbjartsson, Magnus K. Magnusson, Andri Wilberg Orrason
Rok vydání: 2019
Předmět:
Zdroj: Annals of translational medicine. 7(5)
ISSN: 2305-5839
Popis: BACKGROUND: We studied the outcome of pulmonary resection with curative intent for non-small cell lung cancer (NSCLC) in a nationwide study covering a 24-year period, focusing on survival. METHODS: All patients who underwent pulmonary resection for NSCLC in Iceland in the period 1991−2014 were reviewed for demographics, TNM stage and survival. Median length of follow-up was 45 months. Three 8-year periods were compared, overall survival was estimated, and prognostic factors for survival were identified. RESULTS: Altogether, 652 surgical resections were performed on 644 individuals (52% females): 492 lobectomies (75%), 77 pneumonectomies (12%), and 83 sublobar resections (13%). Mean age increased from 65 to 68 yrs during the study period (P=0.002). The number of cases operated at stage IA increased substantially between the first and last periods (29% vs. 37%; P
Databáze: OpenAIRE