Buprenorphine: a treatment and cause of opioid-induced respiratory depression

Autor:	Albert Dahan, Maarten van Lemmen, Simone Jansen, Pieter Simons, Rutger van der Schrier
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Analgesics Opioid Benzodiazepines Anesthesiology and Pain Medicine partial agonism breathing Receptors Opioid mu opioid-induced respiratory depression Humans benzodiazepine Respiratory Insufficiency buprenorphine
Popis:	Buprenorphine is a partial agonist at the mu opioid receptor. Due to its relatively low maximum effect on respiratory depression it is considered by some to be a safe opioid. But it can produce serious respiratory depression, particularly when combined with sedatives such as benzodiazepines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff0de811625b633bba1b83848648110 https://doi.org/10.1016/j.bja.2021.10.029 Zobrazit plný text záznamu