Ultralong Fatty Acyl Derivatives As Occlusive Structure Lipids for Cosmetic Applications: Synthesis and Characterization
| Autor: | Marianne Glasius, Mads Mørk Jensen, Wei Wei, Martyn J. Clarke, Russell Philip Elliot, Anthony V. Rawlings, Mingdong Dong, Pallav A. Bulsara, Shuai Zhang, Zegao Wang, Jason E. Dickens, Bianca Pérez, Zheng Guo |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Renewable Energy Sustainability and the Environment General Chemical Engineering Glyceride Short path distillation Diethylene glycol Langmuir adsorption model General Chemistry 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound symbols.namesake 030104 developmental biology 0302 clinical medicine Differential scanning calorimetry chemistry symbols Glycerol Environmental Chemistry Organic chemistry Molecule Ethylene glycol |
| Zdroj: | Pérez, B, Bulsara, P, Rawlings, A V, Wei, W, Jensen, M M, Wang, Z, Dickens, J, Zhang, S, P. Elliot, R, Glasius, M, Dong, MD, Clarke, M & Guo, Z 2016, ' Ultralong Fatty Acyl Derivatives As Occlusive Structure Lipids for Cosmetic Applications : Synthesis and Characterization ', ACS Sustainable Chemistry & Engineering, vol. 4, no. 12, pp. 7137–7146 . https://doi.org/10.1021/acssuschemeng.6b02021 |
| ISSN: | 2168-0485 |
| DOI: | 10.1021/acssuschemeng.6b02021 |
| Popis: | Finding sustainable and commercially viable sources of occlusive materials, as an alternative to petroleum, is of great interest. Inspired by the fundamental role of long chain fatty acids in maintaining skin barrier, ultralong fatty acyl derivatives with diverse structures (varied acyl chain length and different polar head; i.e. glycerol, ethylene glycol, and diethylene glycol) were synthesized. These molecules can be feasibly obtained via enzymatic esterification of fatty acids or fractionated from commercial glycerides mixture via short path distillation. The molecular packing behaviors of compounds were characterized via differential scanning calorimetry, Fourier transform infrared, and Langmuir isotherm measurements. The structure–property relationship study reveals that a glycerol molecule monoacylated with an ultralong fatty acyl is the derivative which entails the most occlusive properties of the series of ultralong chain fatty acid derivatives. Fast Fourier transform filtering (FFTF) analysis of ... |
| Databáze: | OpenAIRE |
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