Limited Dissemination of Extended-Spectrum β-Lactamase– and Plasmid-Encoded AmpC–Producing Escherichia coli from Food and Farm Animals, Sweden

Autor: Åsa Rosengren, Maria Egervärn, Sofia Ny, Jakob Bergström, Stefan Börjesson, Sara Byfors, Sonja Löfmark, Stina Englund
Jazyk: angličtina
Rok vydání: 2016
Předmět:
0301 basic medicine
bloodstream infections
Swine
Epidemiology
Gene Expression
lcsh:Medicine
Bacteremia
medicine.disease_cause
Plasmid
bacteria
Limited Dissemination of Extended-Spectrum β-Lactamase– and Plasmid-Encoded AmpC–Producing Escherichia coli from Food and Farm Animals
Sweden
Escherichia coli Infections
biology
poultry
digestive
oral
and skin physiology
plasmid-encoded AmpC
extended-spectrum β-lactamase
Enterobacteriaceae
Infectious Diseases
Animals
Domestic
farm animals
Plasmids
Microbiology (medical)
Meat
extended-spectrum cephalosporin
030106 microbiology
beta-Lactamases
Microbiology
lcsh:Infectious and parasitic diseases
pAmpC
03 medical and health sciences
Antibiotic resistance
Bacterial Proteins
medicine
Escherichia coli
Animals
Humans
Food microbiology
lcsh:RC109-216
antimicrobial resistance
Gene
national assessment
Poultry Diseases
carriage
Sweden
broilers
Research
lcsh:R
foodborne infections
biology.organism_classification
030104 developmental biology
Carriage
ESBL
Food Microbiology
Cattle
Chickens
Bacteria
Zdroj: Emerging Infectious Diseases, Vol 22, Iss 4, Pp 634-640 (2016)
Emerging Infectious Diseases
ISSN: 1080-6059
1080-6040
Popis: Food is a limited source of these antimicrobial resistance genes for humans.
Extended-spectrum β-lactamase (ESBL)– and plasmid-encoded ampC (pAmpC)–producing Enterobacteriaceae might spread from farm animals to humans through food. However, most studies have been limited in number of isolates tested and areas studied. We examined genetic relatedness of 716 isolates from 4,854 samples collected from humans, farm animals, and foods in Sweden to determine whether foods and farm animals might act as reservoirs and dissemination routes for ESBL/pAmpC-producing Escherichia coli. Results showed that clonal spread to humans appears unlikely. However, we found limited dissemination of genes encoding ESBL/pAmpC and plasmids carrying these genes from foods and farm animals to healthy humans and patients. Poultry and chicken meat might be a reservoir and dissemination route to humans. Although we found no evidence of clonal spread of ESBL/pAmpC-producing E. coli from farm animals or foods to humans, ESBL/pAmpC-producing E. coli with identical genes and plasmids were present in farm animals, foods, and humans.
Databáze: OpenAIRE
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