Four-dimensional magnetic resonance imaging for the determination of tumour movement and its evaluation using a dynamic porcine lung phantom
| Autor: | F Lohberger, Juergen Biederer, M Fabel, Gregor Remmert, G H Hartmann |
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| Rok vydání: | 2007 |
| Předmět: |
Lung Neoplasms
Materials science Swine Movement Planning target volume In Vitro Techniques Lung pathology Sensitivity and Specificity Signal Imaging phantom Pattern Recognition Automated Imaging Three-Dimensional Porcine lung Image Interpretation Computer-Assisted medicine Animals Radiology Nuclear Medicine and imaging Lung Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Respiratory motion Reproducibility of Results Magnetic resonance imaging Image Enhancement Magnetic Resonance Imaging Artifacts Nuclear medicine business Algorithms Biomedical engineering Motion monitoring |
| Zdroj: | Physics in Medicine and Biology. 52:N401-N415 |
| ISSN: | 1361-6560 0031-9155 |
| DOI: | 10.1088/0031-9155/52/18/n02 |
| Popis: | A method of four-dimensional (4D) magnetic resonance imaging (MRI) has been implemented and evaluated. It consists of retrospective sorting and slice stacking of two-dimensional (2D) images using an external signal for motion monitoring of the object to be imaged. The presented method aims to determine the tumour trajectories based on a signal that is appropriate for monitoring the movement of the target volume during radiotherapy such that the radiation delivery can be adapted to the movement. For evaluation of the 4D-MRI method, it has been applied to a dynamic lung phantom, which exhibits periodic respiratory movement of a porcine heart-lung explant with artificial pulmonary nodules. Anatomic changes of the lung phantom caused by respiratory motion have been quantified, revealing hysteresis. The results demonstrate the feasibility of the presented method of 4D-MRI. In particular, it enables the determination of trajectories of periodically moving objects with an uncertainty in the order of 1 mm. |
| Databáze: | OpenAIRE |
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