Regeneration of skeletal muscles and state of thymus in γ‐irradiated rats under laser therapy of the area of muscle trauma
| Autor: | V S Azarova, N V Bulyakova |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Wound Healing
Pathology medicine.medical_specialty Radiation ulcers business.industry Regeneration (biology) Thymus Gland Anatomy Rats Ionizing radiation Muscle regeneration Laser therapy Gamma Rays Radiation Ionizing Total dose Animals Wounds and Injuries Medicine Surgery Irradiation Low-Level Light Therapy Muscle Skeletal business Wound healing |
| Zdroj: | Minimally Invasive Therapy & Allied Technologies. 15:277-285 |
| ISSN: | 1365-2931 1364-5706 |
| Popis: | The gamma-irradiation of adult rats with a semi-lethal dose (6 Gy) suppressed the posttraumatic regeneration of skeletal muscles and brought about considerable destructive changes in the thymus. The effect of He-Ne laser radiation at a total dose 4.5-5.4 J/cm2 at each operated leg in irradiated rats stimulated the regenerative capacity of skeletal muscle tissue, the healing of skin-muscle wound, and the processes of postradiation recovery in thymus cells (a decrease of chromosome aberrations). The histological structure of regenerates had more muscle pattern. At the same time, the positive dynamics of regenerative processes in muscles was achieved by an increased functional load on the thymus. To stimulate the regeneration of irradiated muscles on the background of a more moderate load on the thymus, the prolonged period of laser therapy and fragmentary distribution of laser exposures during muscle regeneration were preferable. Wound healing improved visibly. Nor formation of chronic radiation ulcers on operated shins was observed. |
| Databáze: | OpenAIRE |
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