Assessment of the New 2012 EULAR/ACR Clinical Classification Criteria for Polymyalgia Rheumatica: A Prospective Multicenter Study

Autor: Ahmet Mesut Onat, Kenan Aksu, Seda Bas, Ozun Bayindir, Necati Çakir, Sema Yilmaz, Ali Ugur Unal, Neslihan Yilmaz, Havva Keskin, Veli Cobankara, Fatma Alibaz-Oner, Pamir Atagündüz, Ayten Yazici, Mehmet Şahin, Gezmiş Kimyon, S. Senel, Ilker Yagci, Meryem Can, B. Kisacik, Sibel Zehra Aydin, Lütfi Akyol, Mehmet Sayarlioglu, Alperen Mengi, Ali Sahin, Haner Direskeneli, Ayse Balkarli, Atalay Dogru, Omer Nuri Pamuk, Gozde Yildirim-Cetin, Nevsun Inanc, Gulsen Ozen, Sule Yasar-Bilge, Sadiye Murat, Kevser Gok, Yonca Cagatay
Přispěvatelé: [Ozen, Gulsen -- Inanc, Nevsun -- Unal, Ali Ugur -- Bas, Seda -- Alibaz-Oner, Fatma -- Atagunduz, Pamir -- Direskeneli, Haner] Marmara Univ, Fac Med, Dept Rheumatol, Muhsin Yazicioglu Str 10, TR-34890 Istanbul, Turkey -- [Yagci, Ilker] Marmara Univ, Fac Med, Dept Phys Therapy & Rehabil, Istanbul, Turkey -- [Murat, Sadiye -- Keskin, Havva] Goztepe Medeniyet Univ, Fac Med, Dept Phys Med & Rehabil, Istanbul, Turkey -- [Can, Meryem -- Mengi, Alperen -- Cakir, Necati] Fatih Sultan Mehmet Educ & Res Hosp, Dept Rheumatol, Istanbul, Turkey -- [Yilmaz, Neslihan -- Cagatay, Yonca] Bilim Univ, Fac Med, Dept Rheumatol, Istanbul, Turkey -- [Kimyon, Gezmis -- Kisacik, Bunyamin -- Onat, Ahmet Mesut] Gaziantep Univ, Fac Med, Dept Rheumatol, Gaziantep, Turkey -- [Balkarli, Ayse -- Cobankara, Veli] Pamukkale Univ, Fac Med, Dept Rheumatol, Denizli, Turkey -- [Yazici, Ayten] Sakarya Educ & Res Hosp, Dept Rheumatol, Sakarya, Turkey -- [Dogru, Atalay -- Sahin, Mehmet] Suleyman Demirel Univ, Dept Rheumatol, Isparta, Turkey -- [Sahin, Ali] Cumhuriyet Univ, Fac Med, Dept Rheumatol, Sivas, Turkey -- [Gok, Kevser -- Senel, Soner] Erciyes Univ, Fac Med, Dept Rheumatol, Kayseri, Turkey -- [Pamuk, Omer Nuri] Trakya Univ, Fac Med, Dept Rheumatol, Edirne, Turkey -- [Yilmaz, Sema] Selcuk Univ, Selcuklu Fac Med, Dept Rheumatol, Konya, Turkey -- [Bayindir, Ozun -- Aksu, Kenan] Ege Univ, Fac Med, Dept Rheumatol, Izmir, Turkey -- [Akyol, Lutfi -- Sayarlioglu, Mehmet] Ondokuz Mayis Univ, Fac Med, Dept Rheumatol, Samsun, Turkey -- [Yildirim-Cetin, Gozde] Sutcu Imam Univ, Fac Med, Dept Rheumatol, Kahramanmaras, Turkey -- [Yasar-Bilge, Sule] Yunus Emre Govt Hosp, Dept Rheumatol, Eskisehir, Turkey -- [Aydin, Sibel Zehra] Univ Ottawa, Sch Med, Dept Rheumatol, Ottawa, ON, Canada, Ozen, Gulsen -- 0000-0002-5423-393X, Ondokuz Mayıs Üniversitesi
Jazyk: angličtina
Rok vydání: 2016
Předmět:
rheumatoid arthritis
Male
Pathology
Classification criteria
2012 European League Against Rheumatism American College of Rheumatology
POLYMYALGIA RHEUMATICA
Arthritis
Rheumatoid

0302 clinical medicine
differential diagnosis
middle aged
pain assessment
Immunology and Allergy
CLASSIFICATION CRITERIA
030212 general & internal medicine
Prospective Studies
Prospective cohort study
Jones criteria
acute phase protein
adult
Area under the curve
clinical trial
Aged
Arthritis
Rheumatoid/*diagnosis

Diagnosis
Differential

Female
Humans
Middle Aged
Polymyalgia Rheumatica/classification/*diagnosis
Sensitivity and Specificity
Shoulder Pain/*diagnosis
Chuang criteria
female
priority journal
classification
Rheumatoid arthritis
diagnostic procedure
prospective study
onset age
musculoskeletal diseases
medicine.medical_specialty
area under the curve
shoulder pain
rheumatic polymyalgia
Immunology
education
disease classification
Article
Polymyalgia rheumatica
03 medical and health sciences
Nobunaga criteria
Rheumatology
Internal medicine
medicine
controlled study
human
intermethod comparison
RHEUMATOID ARTHRITIS
030203 arthritis & rheumatology
controlled clinical trial
business.industry
medicine.disease
discriminant analysis
major clinical study
United States
Highly sensitive
multicenter study
Multicenter study
inflammation
business
Rheumatism
Popis: WOS: 000380854200011
PubMed ID: 26834222
Objective. To assess the performance of the new 2012 provisional European League Against Rheumatism (EULAR)/ American College of Rheumatology (ACR) polymyalgia rheumatica (PMR) clinical classification criteria in discriminating PMR from other mimicking conditions compared with the previous 5 diagnostic criteria in a multicenter prospective study. Methods. Patients older than 50 years, presenting with new-onset bilateral shoulder pain with elevated acute-phase reactants (APR), were assessed for the fulfillment of the new and old classification/diagnostic criteria sets for PMR. At the end of the 1-year followup, 133 patients were diagnosed with PMR (expert opinion) and 142 with non-PMR conditions [69 rheumatoid arthritis (RA)]. Discriminating capacity, sensitivity, and specificity of the criteria sets were estimated. Results. Discriminating capacity of the new clinical criteria for PMR from non-PMR conditions and RA as estimated by area under the curve (AUC) were good with AUC of 0.736 and 0.781, respectively. The new criteria had a sensitivity of 89.5% and a specificity of 57.7% when tested against all non-PMR cases. When tested against all RA, seropositive RA, seronegative RA, and non-RA control patients, specificity changed to 66.7%, 100%, 20.7%, and 49.3%, respectively. Except for the Bird criteria, the 4 previous criteria had lower sensitivity and higher specificity (ranging from 83%-93%) compared with the new clinical criteria in discriminating PMR from all other controls. Conclusion. The new 2012 EULAR/ ACR clinical classification criteria for PMR is highly sensitive; however, its ability to discriminate PMR from other inflammatory/noninflammatory shoulder conditions, especially from seronegative RA, is not adequate. Imaging and other modifications such as cutoff values for APR might increase the specificity of the criteria.
Databáze: OpenAIRE