Lipid temporal trends in normal-weight youth
Autor: | Teniola Shittu, Justin P. Zachariah, Yunfei Wang |
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Rok vydání: | 2021 |
Předmět: |
Male
Pediatric Obesity Adolescent Physiology 030204 cardiovascular system & hematology Article Young Adult 03 medical and health sciences chemistry.chemical_compound Sex Factors 0302 clinical medicine Reference Values Weight loss medicine Humans 030212 general & internal medicine Child Triglycerides Dyslipidemias National health Cholesterol business.industry Body Weight Cholesterol HDL Lipid screening Anthropometry medicine.disease Lipids Obesity Normal weight chemistry Regression Analysis Female lipids (amino acids peptides and proteins) medicine.symptom Cardiology and Cardiovascular Medicine business Dyslipidemia |
Zdroj: | Am Heart J |
ISSN: | 0002-8703 |
Popis: | BACKGROUND: Atherosclerosis begins in youth, partly driven by excess weight(EW) and abnormal lipids. Despite pediatric obesity worsening, lipids improved.Given the relation between EW and abnormal lipids, changes in normal weight (NW) youth may be relevant. We examined the proportions and temporal trendsof youth with abnormal lipids who were NW versus EW. METHODS AND RESULTS: Analysis was done from National Health and Nutrition Examination Surveys (NHANES)1988–2016. Data was extracted for 10–20 year olds measured with anthropometrics and lab testing to determine proportions of NW versus EW with total cholesterol(TC) >190mg/dL, high density lipoprotein cholesterol (HDL-C) 145 mg/dL (N=14,785). In survey-weighted regression analysis, a weight-status interaction term was used to examine effect modification in the lipid temporal trend. Over time, EW prevalence increased while dyslipidemia decreased (trend p value |
Databáze: | OpenAIRE |
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