Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD)
Autor: | Bhushan Patwardhan, Kalpana Joshi, S.P. Mahadik, Anand Pandit, Arti Chaudhary, Bindu Patni, Mrudula Kale, Sheila Bhave, Sagar Lad |
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Rok vydání: | 2006 |
Předmět: |
Male
medicine.medical_specialty Erythrocytes Linseed Oil Antioxidant Nutritional Supplementation medicine.medical_treatment Clinical Biochemistry Pilot Projects Ascorbic Acid Thiobarbituric Acid Reactive Substances chemistry.chemical_compound Rating scale Internal medicine mental disorders Humans Medicine Attention deficit hyperactivity disorder Child Psychiatry Fatty Acids Essential Vitamin C business.industry alpha-Linolenic acid alpha-Linolenic Acid Vitamins Cell Biology medicine.disease Intervention studies Rbc membrane Treatment Outcome Endocrinology chemistry Attention Deficit Disorder with Hyperactivity Dietary Supplements Fatty Acids Unsaturated Drug Therapy Combination Female business |
Zdroj: | Prostaglandins, Leukotrienes and Essential Fatty Acids. 74:17-21 |
ISSN: | 0952-3278 |
DOI: | 10.1016/j.plefa.2005.10.001 |
Popis: | Considerable clinical and experimental evidence now supports the idea that deficiencies or imbalances in certain highly unsaturated fatty acids may contribute to a range of common developmental disorders including Attention Deficit Hyperactivity Disorder (ADHD). Few intervention studies with LCPUFA supplementation have reported inconsistent and marginal results. This pilot study evaluates the effect of alpha linolenic acid (ALA)-rich nutritional supplementation in the form of flax oil and antioxidant emulsion on blood fatty acids composition and behavior in children with ADHD. Post-supplementation levels of RBC membrane fatty acids were significantly higher than pretreatment levels as well as the levels in control. There was significant improvement in the symptoms of ADHD reflected by reduction in total hyperactivity scores of ADHD children derived from ADHD rating scale. |
Databáze: | OpenAIRE |
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