Factors Affecting and Adjustments for Sex Differences in Current Perception Threshold With Transcutaneous Electrical Stimulation in Healthy Subjects
Autor: | Shin-ichiro Seno, Atsushi Watanabe, Hiroko Kobayashi, Hideaki Shimazu, Eiki Kogure |
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Rok vydání: | 2019 |
Předmět: |
Adult
Male sex differences Body water Sensation Physiology Stimulation Body fat percentage current perception threshold Young Adult 03 medical and health sciences 0302 clinical medicine Clinical Research Humans Medicine electrical stimulation Pain Measurement Sex Characteristics business.industry Healthy subjects Transcutaneous Electrical Stimulation General Medicine body fat percentage Healthy Volunteers Sensory function Anesthesiology and Pain Medicine PERIPHERAL NERVE STIMULATION Neurology Sensory Thresholds Transcutaneous Electric Nerve Stimulation Female Neurology (clinical) business 030217 neurology & neurosurgery |
Zdroj: | Neuromodulation |
ISSN: | 1094-7159 |
Popis: | Objective Current perception threshold (CPT) measurement is a noninvasive, easy, and semi‐objective method for determining sensory function using transcutaneous electrical stimulation. Previous studies have shown that CPT is determined by physical characteristics, such as sex, age, physical sites, and presence of neuropathy. Although the CPT reported in males is clearly higher than that in females, the reason for this difference remains unclear. This study investigates the cause of sex‐based differences in CPT and suggests an adjustment method, which may suppress the sex difference in CPT. Materials and Methods Electrical stimulation was applied with PainVision® via five sizes of circular surface electrodes. Seventy healthy participants were examined thrice under each electrode. The relationship among body water percentage, body fat percentage, and CPT was then analyzed. Results CPT values are higher in males than that in females, with statistically significant sex differences with each electrode pairs (EL 1: p < 0.001; EL 2: p = 0.006; EL 3: p < 0.001; EL 4: p < 0.001; EL 5: p < 0.001). By adjusting for body fat percentage or body water percentage, the log‐transformation values (CPT values) no longer exhibit sex differences with any electrode pairs (body fat: p = 0.09; body water: p = 0.08). Conclusion We conclude that sensitivity for perceiving electrical stimulation can be influenced by the subjects' characteristics, such as body fat or body water percentages. |
Databáze: | OpenAIRE |
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