Prevalence and risk factors of hepatitis B and C virus infections among the general population and blood donors in Morocco
| Autor: | Abdelouaheb Bennani, Fatiha Lazar, Noureddine Dersi, Soumaya Benjelloun, Bouchra Oukkache, Hassan Mifdal, My Mustapha Ennaji, Khadija El alaoui, Warda Baha, Nadia Nourichafi, Abdelouhad Elmalki, Abderrahim Foullous, Thierry Paluku They-they |
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| Jazyk: | angličtina |
| Předmět: |
Adult
Male HBsAg medicine.medical_specialty Adolescent Hepatitis C virus Population Blood Donors medicine.disease_cause Young Adult Renal Dialysis Risk Factors Internal medicine Prevalence medicine Humans Child education Aged Aged 80 and over Hepatitis B virus Hepatitis Cross Infection education.field_of_study Hepatitis B Surface Antigens business.industry Public Health Environmental and Occupational Health virus diseases General population Hepatitis C Hepatitis C Antibodies Middle Aged Hepatitis B medicine.disease digestive system diseases Morocco Cross-Sectional Studies Child Preschool Population Surveillance Immunology Female Viral hepatitis business Research Article |
| Zdroj: | BMC Public Health |
| ISSN: | 1471-2458 |
| DOI: | 10.1186/1471-2458-13-50 |
| Popis: | BackgroundViral hepatitis is a serious public health problem affecting billions of people globally. Limited information is available on this issue in Morocco. This cross-sectional study was undertaken with the aim of determining the seroprevalence and risk factors of hepatitis B virus (HBV) and hepatitis C virus (HCV) among the general population and among blood donors.MethodsBlood samples from volunteers, have been screened with ELISA tests for detecting the hepatitis-B surface antigen (HBsAg) and anti-HCV. Within the seroreactive patients for HCV in the general population, RT-PCR was performed by the Cobas Ampliprep/Cobas Amplicor.ResultsHCV and HBV-seropositivity was documented in 1.58% and 1.81% out of 41269 and 23578 participants respectively from the general population. Two patients were found to be co-infected. HCV-RNA was detected by PCR in 70.9% of the 195 anti-HCV positive subjects. The anti-HCV prevalence was not different among males and females (P = 0.3). It increased with age; the highest prevalence was observed among subjects with >50 years old (3.12%). Various risk factors for acquiring HCV infection were identified; age, dental treatment, use of glass syringes and surgical history. In addition to these factors, gender and sexual risk behaviors were found to be associated with higher prevalence of hepatitis B. The HBV positivity was significantly higher among males than females participants in all age groups (P ConclusionsOur study provided much important information concerning hepatitis B and C prevalence and risk factors; it confirmed the intermediate endemicity for HCV infection and pointed to a decreasing trend of HBV incidence, which might reclassify Morocco in low HBV endemicity area. This could be attributed primarily to the universal HBV vaccination among infants and healthcare workers over the past 13 years. HCV and HBV infections in the present survey were mainly associated with nosocomial exposures. Prevention and control of HBV infection are needed to reduce HBV transmission between adults. |
| Databáze: | OpenAIRE |
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