Effect of SPIO Nanoparticle Concentrations on Temperature Changes for Hyperthermia via MRI
| Autor: | Ahmed A G El-Shahawy, Alsayed A. M. Elsherbini |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Hyperthermia
Materials science Article Subject Heat energy Specific absorption rate Cellular level medicine.disease Paramagnetism Nuclear magnetic resonance SPIO Nanoparticle lcsh:Technology (General) medicine Magnetic nanoparticles lcsh:T1-995 General Materials Science Thermal damage Biomedical engineering |
| Zdroj: | Journal of Nanomaterials, Vol 2013 (2013) |
| ISSN: | 1687-4129 1687-4110 |
| Popis: | Magnetic nanoparticles (MNPs) are being developed for a wide range of biomedical applications. In particular, hyperthermia involves heating the MNPs through exposure to an alternating magnetic field (AMF). These materials offer the potential for selectively by heating cancer tissue locally and at the cellular level. This may be a successful method if there are enough particles in a tumor possessing sufficiently high specific absorption rate (SAR) to deposit heat quickly while minimizing thermal damage to surrounding tissue. The current research aim is to study the influence of super paramagnetic iron oxides Fe3O4(SPIO) NPs concentration on the total heat energy dose and the rate of temperature change in AMF to induce hyperthermia inEhrlichcarcinoma cells implanted in female mice. The results demonstrated a linearly increasing trend between these two factors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text