A new evidence-based risk stratification system for cutaneous squamous cell carcinoma into low, intermediate, and high risk groups with implications for management
| Autor: | Christian L. Baum, Randall K. Roenigk, Adam C. Wright, Juan Carlos Martinez, Jerry D. Brewer, Christopher J. Arpey, Clark C. Otley |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Oncology medicine.medical_specialty Skin Neoplasms Cutaneous squamous cell carcinoma Evidence-based practice Chronic lymphocytic leukemia medicine.medical_treatment Perineural invasion Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Risk groups Internal medicine Humans Medicine Neoplasm Invasiveness Aged Evidence-Based Medicine business.industry Nodal metastasis Biopsy Needle Disease Management Middle Aged Prognosis medicine.disease Immunohistochemistry Survival Analysis United States Radiation therapy Lymphatic Metastasis 030220 oncology & carcinogenesis Risk stratification Carcinoma Squamous Cell Lymph Node Excision Female Risk Adjustment Lymph Nodes business |
| Zdroj: | Journal of the American Academy of Dermatology. 78:141-147 |
| ISSN: | 0190-9622 |
| Popis: | Most primary cutaneous squamous cell carcinomas are cured with surgery. A subset, however, may develop local and nodal metastasis that may eventuate in disease-specific; death. This subset has been variably termed high risk. Herein, we review; an emerging body of data on the risks of these outcomes and propose an evidence-based; risk stratification for low-, intermediate-, and high-risk tumors that takes into; account both tumor and patient characteristics. Finally, we discuss a framework for; management of these tumors on the basis of data, when available, and our; recommendations when data are sparse. |
| Databáze: | OpenAIRE |
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