Genital Human Papillomavirus Infection in Panama City Prostitutes
| Autor: | Marina Cuevas, Deoraj Caussy, Suzanne Loo de Lao, Juan Ramon Arosemena, William C. Reeves, Evelia Quiroz, William E. Rawls, Mariana Garcia |
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| Rok vydání: | 1989 |
| Předmět: |
Adult
Adolescent Panama Sexual Behavior Virus Cohort Studies Interviews as Topic Uterine Cervical Diseases Recurrence Risk Factors Genital Human Papillomavirus Infection medicine Humans Immunology and Allergy Sex organ Longitudinal Studies Papillomaviridae business.industry HPV infection Nucleic Acid Hybridization Middle Aged medicine.disease Sex Work Virology Natural history Tumor Virus Infections Infectious Diseases DNA Viral Multiple sampling Cohort Female business |
| Zdroj: | Journal of Infectious Diseases. 160:599-603 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/160.4.599 |
| Popis: | Little is known of the natural history of genital human papillomavirus (HPV) infections in women from high-risk populations. Samples were collected from 183 Panama City prostitutes and assessed for HPV (filter in situ DNA hybridization) and for sexually transmitted agents. The cohort was followed for 8 mo; 51% of subjects completed four monthly return visits and 16% were sampled eight times. The proportion of women found infected with HPV increased significantly with increasing numbers of consecutive samples tested; 38 (21%) of 183 women were positive after one visit and 46 (82%) of 56 who completed six visits were infected. The pattern of viral detection over time was not random, which implied that most prostitutes were persistently infected with genital HPVs and that either scattered foci of infection or periodic reactivation of latent virus occurred. Our findings suggest that multiple sampling is necessary to accurately estimate HPV infection rates and to define whether patterns of DNA expression are present. |
| Databáze: | OpenAIRE |
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