Sero-prevalence of hepatitis B virus and hepatitis C virus among HIV patients in a suburban University Teaching Hospital in South-East Nigeria
Autor: | Jerome Emeka Azike, Nathan Chibuzo Nwaimo, E C Okwara, Chiekulie Kevin Diwe, Oguamanam Okezie Enwere |
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Jazyk: | angličtina |
Rok vydání: | 2013 |
Předmět: |
Adult
Male Hepatitis B virus HBsAg medicine.medical_specialty Hepatitis C virus Nigeria HIV Infections hiv Hepacivirus medicine.disease_cause co-infection Acquired immunodeficiency syndrome (AIDS) Seroepidemiologic Studies Internal medicine medicine hcv Humans Seroprevalence Hospitals Teaching lcsh:R5-920 seroprevalence Coinfection business.industry Research lcsh:Public aspects of medicine virus diseases lcsh:RA1-1270 General Medicine Hepatitis C Middle Aged Hepatitis B medicine.disease Virology digestive system diseases hbv Female business liver disease lcsh:Medicine (General) |
Zdroj: | The Pan African Medical Journal, Vol 16, Iss 7 (2013) Pan African Medical Journal; Vol 16, No 1 (2014) The Pan African Medical Journal |
ISSN: | 1937-8688 |
Popis: | Introduction : Highly active antiretroviral therapy (HAART) has improved survival of human immunodeficiency virus (HIV) patients. Concurrent morbidities from liver diseases among these patients have also been observed due to co-infection with hepatitis B and C viruses (HBV and HCV). HAART reduces liver-associated morbidities and mortalities in such patients. Unfortunately free testing of HBV and HCV are not provided alongside free HIV testing and treatment in Nigeria. We assessed the seroprevalence of HBV and HCV among HIV patients presenting for treatment in our center. Methods : This prospective study of adult patients with HIV/AIDS assessed the seroprevalence of HBV and HCV co-infection using a 19- item questionnaire and collection of 2ml venous blood for hepatitis B surface antigens (HBsAg) and anti-HCV antibodies. All previously diagnosed HIV patients of the unit were excluded from the study. Results : Of the 404 patients, 69.2% were females while 30.8% were males. Married participants were 59.6%, 25.3% were single and 15% were previously married. A large proportion (69%) of patients were farmers, artisans and traders. Most had some formal education; secondary (55.3%), primary 27.3%, tertiary 13.8%. HBsAg positive participants were 9 (2.2%) while 3 (0.7%) were positive for HCV. No participant had triple infection of HIV/HBV/HCV. Conclusion : Seroprevalence of HBV and HCV is low among HIV patients in Orlu. However there is a need for HBV and HCV testing of all HIV positive patients to reduce morbidities and mortalities from liver diseases. |
Databáze: | OpenAIRE |
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