Type 1 diabetes in children and adolescents is not associated with a reduced prevalence of atopy and allergic diseases
| Autor: | Alexander Avian, Julia Hontzsch, Lisa Pieringer, Elisabeth Suppan, Hildegard Jasser-Nitsche, Gudrun Weinhandl, Helmuth Martin Borkenstein, Elke Fröhlich-Reiterer, Eva-Maria Varga |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Allergy Pediatrics medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism Population Breastfeeding 030209 endocrinology & metabolism Allergic sensitization Atopy Cohort Studies 03 medical and health sciences 0302 clinical medicine Diabetes mellitus Internal Medicine medicine Hypersensitivity Prevalence Animals Humans 030212 general & internal medicine education Child Type 1 diabetes education.field_of_study business.industry Pets Immunoglobulin E medicine.disease Breast Feeding Diabetes Mellitus Type 1 Austria Case-Control Studies Pediatrics Perinatology and Child Health Female business Cohort study |
| Zdroj: | Pediatric diabetes. 18(8) |
| ISSN: | 1399-5448 |
| Popis: | Background Type 1 diabetes mellitus (T1D) as well as allergies in childhood have increased worldwide during the last 2 decades. The reasons for this increase are still unknown but early life origins are being discussed, such as dietary and hygiene factors that may play a role in the development of both diseases. The aim of this study was to compare the prevalence of allergies in children with and without T1D and to define potential influencing factors. Materials and Methods Data were collected from 104 patients with T1D (n = 104; mean age 11.4 ± 4.4 years; m/f: 77/27) and 104 healthy controls (CG) (n = 104; mean age 11.4 ± 4.3 years; m/f: 77/27). A questionnaire on allergic symptoms was obtained from each individual. In parallel, ImmunoCAP tests to detect specific allergen sensitization were performed. Results Allergen sensitization rates were not significantly different between both groups (T1D: 42% vs CG 38%; P = 0.625). In both groups, a comparable number of patients reported allergic symptoms in the questionnaire (T1D: 20% vs CG 26%; P = 0.43). Allergen sensitization and allergic symptoms were independent of breastfeeding, pets at home or diabetes duration. However, in T1D, fewer family members smoked (T1D: 10% vs CG 56%; P |
| Databáze: | OpenAIRE |
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