Delayed diagnosis of bullous pyoderma gangrenosum with acute myelogenous leukemia

Autor: Serpil Sener, Gülbahar Saraç, Nihal Altunisik, Y Bayindir
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nigerian Journal of Clinical Practice; Vol 19, No 6 (2016); 837-839
ISSN: 1119-3077
Popis: Pyoderma gangrenosum (PG) is a rare, but serious neutrophilic dermatosis characterized by recurrent painful cutaneous ulcerations. It is commonly associated with inflammatory bowel disease, rheumatoid arthritis, and hematological malignancies. Because laboratory evaluations and histologic features of PG are nonspecific, diagnosis is based on the clinical features of the ulcer and requires exclusion of other conditions that cause such ulceration. The disease responds to glucocorticoids, immunosuppressives, and anti‑inflammatory drugs. We present a 30‑year‑old man with acute myelogenous leukemia (subtype M5) and bullous PG. Treatment with high‑dose prednisolone was successful.Keywords: Acute myelogenous leukemia, bullous pyoderma gangrenosum, leukemia and pyoderma gangrenosum
Databáze: OpenAIRE