Crib death: further support for the concept of fatal cardiac electrical instability as the final common pathway
| Autor: | Lino Rossi, Luigi Matturri, Thomas N. James, Giulia Ottaviani |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Heart disease business.industry Heart block Myocardium Infant Apoptosis medicine.disease Sudden death Hypoplasia Surgery Long QT Syndrome Junctional tachycardia Heart Conduction System Heart failure Internal medicine Cardiac conduction cardiovascular system medicine Cardiology Humans Electrical conduction system of the heart Cardiology and Cardiovascular Medicine business Sudden Infant Death |
| Zdroj: | International Journal of Cardiology. 92:17-26 |
| ISSN: | 0167-5273 |
| Popis: | This work intends to be a review of the current status of knowledge on the cardiac conduction system in the crib death as well as remaining challenges, including reflections upon authors' personal works as well as many studies by others. The cardiac conduction system findings of resorptive degeneration, His bundle dispersion, Mahaim fibers, cartilaginous meta-hyperplasia, persistent fetal dispersion, left sided His bundle, hemorrhage of the atrio-ventricular junction, septation of the bifurcation, atrio-ventricular node dispersion, sinus node hypoplasia, Zahn node, His bundle hypoplasia, atrio-ventricular node and His bundle dualism are hereby discussed by the authors. The cardiac hypotheses postulating that crib death could be due to lethal cardiac arrhythmias or heart block were considered of great interest in the 1970s. After a general abandon of the conduction studies in crib death, the cardiac concept of crib death is gathering a renewed interest, as well as the occurrence of infantile junctional tachycardia. Both the morphological and functional derangement underlying crib death remain poorly understood, assuring that it remains to be a major medical and social problem. Despite the non-specificity of most of the cardiac conduction findings in crib death, we believe that they, in association with altered neurovegetative stimuli, could underlie potentially malignant arrhythmias, providing a morphologic support for the cardiac concept of crib death. |
| Databáze: | OpenAIRE |
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