Inadequacy of intravenous heparin therapy in the initial management of venous thromboembolism

Autor: Derek King, Julian Dobranowski, Gordon H. Guyatt, Alicia Sarabia, Peter Powers, Deborah J. Cook, Hui N. Lee, Annette McCallum, Rose Hatala
Rok vydání: 1995
Předmět:
Zdroj: Journal of General Internal Medicine. 10:342-345
ISSN: 1525-1497
0884-8734
DOI: 10.1007/bf02599954
Popis: To determine the adequacy of initial anticoagulation by intravenous heparin for patients who have deep venous thrombosis (DVT), and the factors that influence delayed anticoagulation, independent, duplicate chart review of 63 consecutive patients who had venography-proven DVT was conducted. Adequate heparinization (AH) was defined as an activated partial thromboplastin time (PTT) of more than 1.5 times the normal laboratory control. The proportions of patients achieving AH within 24 hours and 48 hours of initial heparin bolus were 46% and 62%, respectively. Patients who weighed more were less likely to achieve AH (p
Databáze: OpenAIRE