Inadequacy of intravenous heparin therapy in the initial management of venous thromboembolism
Autor: | Derek King, Julian Dobranowski, Gordon H. Guyatt, Alicia Sarabia, Peter Powers, Deborah J. Cook, Hui N. Lee, Annette McCallum, Rose Hatala |
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Rok vydání: | 1995 |
Předmět: |
medicine.drug_class
medicine.medical_treatment Bolus (medicine) Internal Medicine medicine Humans Infusions Intravenous Aged Retrospective Studies Chemotherapy medicine.diagnostic_test Heparin Vascular disease business.industry Anticoagulant Thrombophlebitis Nomogram medicine.disease Venous thrombosis Treatment Outcome Anesthesia Multivariate Analysis Practice Guidelines as Topic business Partial thromboplastin time medicine.drug |
Zdroj: | Journal of General Internal Medicine. 10:342-345 |
ISSN: | 1525-1497 0884-8734 |
DOI: | 10.1007/bf02599954 |
Popis: | To determine the adequacy of initial anticoagulation by intravenous heparin for patients who have deep venous thrombosis (DVT), and the factors that influence delayed anticoagulation, independent, duplicate chart review of 63 consecutive patients who had venography-proven DVT was conducted. Adequate heparinization (AH) was defined as an activated partial thromboplastin time (PTT) of more than 1.5 times the normal laboratory control. The proportions of patients achieving AH within 24 hours and 48 hours of initial heparin bolus were 46% and 62%, respectively. Patients who weighed more were less likely to achieve AH (p |
Databáze: | OpenAIRE |
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