Suspected tolazoline toxicosis in a llama
| Autor: | Matt R. Read, Tanya Duke, Anne R. Toews |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Insufflation
Xylazine Sedation Tachypnea Injections Intramuscular Phenylephrine Seizures Nose Diseases medicine Animals Edema Hypnotics and Sedatives Tolazoline Adrenergic alpha-Antagonists Gastrointestinal tract Diazepam General Veterinary business.industry Oxygen Inhalation Therapy Hyperesthesia Nasal Decongestants Anesthesia Injections Intravenous Fluid Therapy Anticonvulsants Female medicine.symptom Tracheotomy business Adrenergic alpha-Agonists Camelids New World medicine.drug |
| Zdroj: | Journal of the American Veterinary Medical Association. 216(2) |
| ISSN: | 0003-1488 |
| Popis: | Clinical signs of tolazoline toxicosis developed in a 4-year-old llama that received 2 doses of tolazoline hydrochloride to reverse xylazine-induced sedation. The full first dose (4.3 mg/kg [2.0 mg/lb] of body weight) was erroneously injected i.v., and the second dose was administered half i.v., half i.m. 45 minutes later, because the llama became weak and recumbent. Signs of anxiety, hyperesthesia, profuse salivation, and tachypnea were the first detectable clinical signs of tolazoline toxicosis. Convulsions, hypotension, gastrointestinal tract hypermotility, and diarrhea also developed. The llama was treated successfully with i.v. administration of diazepam, phenylephrine, and lactated Ringer's solution supplemented with potassium chloride and oxygen administered via nasal insufflation. We suggest that the maximum dose of tolazoline administered at any one time to llamas not exceed 2 mg/kg (0.91 mg/lb). Furthermore, tolazoline should be administered slowly i.v. or i.m. to reduce the risk of adverse reactions. |
| Databáze: | OpenAIRE |
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