Prevalence of thyroid dysfunction and its correlation with CD4 count in newly-diagnosed HIV-positive adults – a cross-sectional study
| Autor: | Nishanth Dev, Ratnakar Sahoo, Bindu Kulshreshtha, Sourabh Sharma, Adesh Kisanji Gadpayle |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Thyroid Hormones Pediatrics medicine.medical_specialty Cross-sectional study Thyroid Gland Thyrotropin Enzyme-Linked Immunosorbent Assay HIV Infections Dermatology Thyroid Function Tests Hyperthyroidism Correlation Hypothyroidism Thyroid-stimulating hormone Acquired immunodeficiency syndrome (AIDS) Prevalence medicine Humans Endocrine system Pharmacology (medical) Subclinical infection business.industry Thyroid Public Health Environmental and Occupational Health Middle Aged medicine.disease Thyroid Diseases Anti-thyroid autoantibodies CD4 Lymphocyte Count Thyroxine Cross-Sectional Studies Infectious Diseases medicine.anatomical_structure Case-Control Studies Immunology Triiodothyronine Female business |
| Zdroj: | International Journal of STD & AIDS. 26:965-970 |
| ISSN: | 1758-1052 0956-4624 |
| DOI: | 10.1177/0956462414563776 |
| Popis: | Prevalence of subclinical hypothyroidism in HIV-positive patients is reported to be high in those with severe immune deficiency. However, there is paucity of literature in newly-diagnosed HIV-positive population. Our aim was to estimate the prevalence of thyroid dysfunction and study its correlation with CD4 count in this population. In this cross-sectional study, patients presenting to the antiretroviral therapy clinic were screened with thyroid function tests, including thyroid stimulating hormone, free triiodothyronine, free thyroxine, and anti-thyroid peroxidase antibody levels at the time of diagnosis. Two hundred and twenty-five HIV-positive and an equal number of healthy volunteers were enrolled. The mean (SD) CD4 count in the study group was 147.1 (84) and 70.7% had advanced immune deficiency with CD4 count |
| Databáze: | OpenAIRE |
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