Host Peptidic Hormones Affecting Bacterial Biofilm Formation and Virulence
| Autor: | Sophie Rodrigues, Mélissande Louis, Thibaut Rosay, Pierre Cornelis, Emeline Bouffartigues, Marc G. J. Feuilloley, Florie Desriac, A. V. Gannesen, Alexis Bazire, Sylvie Chevalier, Ali Tahrioui, Vladimir K. Plakunov, Alain Dufour, Thomas Clamens, Olivier Lesouhaitier |
|---|---|
| Přispěvatelé: | Laboratoire de Microbiologie Signaux et Microenvironnement (LMSM), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Russian Academy of Sciences [Moscow] (RAS), Lomonosov Moscow State University (MSU), Laboratoire de Biotechnologie et Chimie Marines (LBCM), Université de Bretagne Sud (UBS)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM), Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.drug_class Calcitonin Gene-Related Peptide Peptide Hormones Antibiotics Virulence Biology medicine.disease_cause Gram-Positive Bacteria Dynorphins Microbiology 03 medical and health sciences 0302 clinical medicine Gram-Negative Bacteria medicine Immunology and Allergy Humans Natriuretic Peptides ComputingMilieux_MISCELLANEOUS Pseudomonas aeruginosa Host (biology) Neuropeptides Biofilm biology.organism_classification [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology 3. Good health 030104 developmental biology 030228 respiratory system Biofilms Somatostatin Bacteria Hormone |
| Zdroj: | Journal of Innate Immunity Journal of Innate Immunity, Karger, 2018, pp.1-15. ⟨10.1159/000493926⟩ Journal of Innate Immunity, 2018, pp.1-15. ⟨10.1159/000493926⟩ |
| ISSN: | 1662-811X 1662-8128 |
| DOI: | 10.1159/000493926⟩ |
| Popis: | Bacterial biofilms constitute a critical problem in hospitals, especially in resuscitation units or for immunocompromised patients, since bacteria embedded in their own matrix are not only protected against antibiotics but also develop resistant variant strains. In the last decade, an original approach to prevent biofilm formation has consisted of studying the antibacterial potential of host communication molecules. Thus, some of these compounds have been identified for their ability to modify the biofilm formation of both Gram-negative and Gram-positive bacteria. In addition to their effect on biofilm production, a detailed study of the mechanism of action of these human hormones on bacterial physiology has allowed the identification of new bacterial pathways involved in biofilm formation. In this review, we focus on the impact of neuropeptidic hormones on bacteria, address some future therapeutic issues, and provide a new view of inter-kingdom communication. |
| Databáze: | OpenAIRE |
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