The plant molluscicide Millettia thonningii (Leguminosae) as a topical antischistosomal agent
| Autor: | Lisa Sanderson, Philip J. Whitfield, S. Perrett, A. Bartlett |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Molluscacides
Administration Topical Biology Pharmacognosy chemistry.chemical_compound Mice Isoflavonoid parasitic diseases Drug Discovery medicine Animals Millettia thonningii Anthelmintic Chromatography High Pressure Liquid Skin Pharmacology Flavonoids Plants Medicinal Traditional medicine Plant Extracts Fabaceae Schistosoma mansoni Alpinumisoflavone biology.organism_classification Schistosomiasis mansoni chemistry Solubility Molluscicide Seeds Female Spectrophotometry Ultraviolet medicine.drug |
| Zdroj: | Journal of ethnopharmacology. 47(1) |
| ISSN: | 0378-8741 |
| Popis: | The West African legume Millettia thonningii is used in Ghana as an anthelmintic and as a purgative agent. A chloroform extract of the seeds of Millettia thonningii which is known to be molluscicidal and cercaricidal was topically applied to mouse skin 2 and 24 h prior to exposure to Schistosoma mansoni cercariae. The presence of Millettia thonningii extract components on the surface of the skin appeared to be effective in preventing subsequent establishment of infection. The compound responsible for the activity is thought to be the isoflavonoid alpinumisoflavone. |
| Databáze: | OpenAIRE |
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