Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning
| Autor: | Barbara Kit, Tadej Petreski, Franc Svenšek, Matej Strnad, Damjan Grenc |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Obidoxime Pediatrics medicine.medical_specialty Case Report Physical examination 010501 environmental sciences Toxicology 01 natural sciences carbofuran obidoksim 03 medical and health sciences chemistry.chemical_compound CHOLINERGIC SYNDROME medicine obidoxime chlormephos klormefos 0105 earth and related environmental sciences Cholinesterase biology medicine.diagnostic_test business.industry Carbamate poisoning Organophosphate Public Health Environmental and Occupational Health intenzivna medicina Acetylcholinesterase critical care Chlormephos karbofuran 030104 developmental biology chemistry biology.protein business medicine.drug |
| Zdroj: | Archives of Industrial Hygiene and Toxicology |
| ISSN: | 1848-6312 |
| DOI: | 10.2478/aiht-2020-71-3413 |
| Popis: | Cholinergic syndrome is a common topic at western medical universities yet rarely observed in clinical practice. The treatment involves muscarinic antagonists, acetylcholinesterase reactivation, seizure control, and supportive measures. Here we report a case of a 52-year old Caucasian male who attempted suicide by ingesting a purple crystal powder that turned out to be a mixture of carbofuran and chlormephos. At clinical examination, the patient presented with salivation, perspiration, diarrhoea, bradypnoea, loss of consciousness, and epileptic seizures. Laboratory tests showed low plasma cholinesterase, and we started obidoxime along with supportive intensive care treatment. He was later transferred to the psychiatry department for further diagnostics and treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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