Maternal and fetal risk factors affecting perinatal mortality in early and late fetal growth restriction

Autor: Selçuk Selçuk, Bülent Tandoğan, Zafer Bütün, Pınar Kumru, Resul Arisoy, Gürcan Türkyilmaz, Didar Mahmutoğlu, Barış Boza, Mehmet Resit Asoglu, Oya Demirci
Rok vydání: 2015
Předmět:
Zdroj: Taiwanese Journal of Obstetrics & Gynecology, Vol 54, Iss 6, Pp 700-704 (2015)
ISSN: 1875-6263
Popis: Objective To determine the factors which affect the perinatal deaths in early and late fetal growth restriction (FGR) fetuses using threshold of estimated fetal weight (EFW) th percentile. Materials and Methods This retrospective study included singleton 271 FGR fetuses, defined as an EFW th percentile. All fetuses considered as growth restrictions were confirmed by birth weight. Fetuses with multiple pregnancy, congenital malformation, chromosomal abnormality, and premature rupture of membrane were excluded. Samples were grouped in early and late FGR. Early FGR fetuses was classified as gestational age at birth ≤ 34 weeks and late FGR was classified as gestational age at birth > 34 weeks. Factors which affect the perinatal deaths were analyzed descriptively in early and late FGR. The perinatal mortality was calculated by adding the number of stillbirths and neonatal deaths. Results The study included 86 early and 185 late FGR fetuses, 31 resulted in perinatal deaths, 28 perinatal deaths were in early FGR, and three perinatal deaths were in late FGR. Perinatal deaths occurred more commonly in early FGR fetuses with an EFW rd percentile. Prior stillbirth, preeclampsia, the degree of increasing vascular impedance of umbilical artery(UA) and uterine artery (UtA) showed significant correlation with perinatal death in early FGR. All three perinatal deaths in late FGR occurred in fetuses with EFW rd percentile and severe oligohydramnios. Also, placental abruption and perinatal death was found significantly higher in increased vascular impedance of UtAs whatever the umbilical artery Doppler. Conclusion Only EFW rd percentile and severe olgohydramnios seem to be contributing factors affecting perinatal death in late FGR in comparison with early FGR.
Databáze: OpenAIRE