Nitrosamine Formation in Bladder Infections and its Role in the Etiology of Bladder Cancer
| Autor: | J L, Radomski, D, Greenwald, W L, Hearn, N L, Block, F M, Woods |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
medicine.medical_specialty
Nitrosamines Urology Urinary system Urine medicine.disease_cause Dimethylnitrosamine chemistry.chemical_compound medicine Humans Escherichia coli Carcinogen Bladder cancer biology business.industry Urinary Bladder Diseases medicine.disease biology.organism_classification Proteus mirabilis Urinary Bladder Neoplasms chemistry Tetracyclines Nitrosamine Urinary Tract Infections Etiology Cancer research business |
| Zdroj: | Journal of Urology. 120:48-50 |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1016/s0022-5347(17)57035-4 |
| Popis: | Dimethylnitrosamine, a powerful carcinogen, is produced in the urine of patients with urinary tract infections of Proteus mirabilis and Escherichia coli when nitrite is present. Treatment with tetracycline antibiotics does not enhance the concentration of this carcinogen but, rather, sharply reduces it. The results emphasize the importance of proper antibiotic therapy for the infections to reduce the possibility of the subsequent development of bladder cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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