Sustained low-efficiency diafiltration is superior to hemodialysis in promoting renal function recovery in elderly wasp sting victims with stage III acute kidney injury: a retrospective study

Autor: Jian-Ming Shen, Wen-Wen Li, Rong Gou, Ting-Ting Ye, Yan-Yan Deng, Ya-Ni Mao
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
medicine.medical_specialty
medicine.medical_treatment
Wasps
030232 urology & nephrology
Urology
Renal function
Wasp Venoms
030204 cardiovascular system & hematology
Critical Care and Intensive Care Medicine
Kidney
03 medical and health sciences
wasp stings
0302 clinical medicine
Sustained low-efficiency diafiltration
Renal Dialysis
medicine
Animals
Humans
Stage (cooking)
APACHE
Aged
Retrospective Studies
hemodialysis
business.industry
renal function
Wasp sting
Acute kidney injury
Insect Bites and Stings
Retrospective cohort study
General Medicine
Recovery of Function
Acute Kidney Injury
Middle Aged
medicine.disease
eye diseases
Diseases of the genitourinary system. Urology
Diafiltration
medicine.anatomical_structure
Treatment Outcome
Nephrology
Creatinine
Clinical Study
Female
Hemodialysis
RC870-923
business
Zdroj: Renal Failure
Renal Failure, Vol 41, Iss 1, Pp 814-820 (2019)
ISSN: 1525-6049
0886-022X
Popis: Objective: To study the efficacy and safety of sustained low-efficiency diafiltration (SLEDf) versus hemodialysis (HD) for patients with wasp stings who developed stage III acute kidney injury (AKI). Methods: We retrospectively analyzed the clinical data of consecutive patients who developed AKI following wasp stings. All eligible patients received renal replacement therapy in combination with hemoperfusion. Thereafter, blood purification therapy and HD were performed with a volumetrically controlled machine and 1.7 m2 surface, Fresenius Polysulfone HD filter and SLEDf was undertaken with a volumetrically controlled machine and 1.3 m2 surface, Fresenius Polysulfone HD filter. Results: Forty patients developed stage III AKI following wasp stings, including 14 patients that received SLEDf and 26 patients underwent HD. Thirteen patients were aged less than 60 years and underwent HD (group I), 27 patients were aged at least 60 years, including 13 patients undergoing HD (group II) and 14 patients receiving SLEDf (group III). Groups I and II completed 150 and 162 sessions of HD, respectively, and group III completed 156 sessions of sustained low-efficiency blood purification therapy, including 50 sessions of SLEDf. The time to return to normal serum creatinine levels was 38.8 ± 2.7 days for group I, 47.2 ± 5.3 days for group II, and 39.2 ± 3.3 days for group III. A statistically significant difference was observed in time to normal serum creatinine levels among the three groups. Conclusion: Elderly wasp victims have more severe illness than younger wasp victims and SLEDf is safe and superior to HD in recovery of renal function of elderly wasp victims.
Databáze: OpenAIRE
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