Immunohistochemistry for the Differentiation of Peritoneal Disseminated Carcinoma of Unknown Origin
| Autor: | Tae Sato, Masaru Suzuki, Atsuko Miyaji, Toshiharu Matsumoto, Akihiko Ohwada, Ryoichiro Miyazaki |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Pathology
medicine.medical_specialty Adenocarcinoma Peritonitis Risk Assessment Diagnosis Differential Neoplasms Multiple Primary Ovarian tumor Carcinoembryonic antigen Pancreatic tumor Antineoplastic Combined Chemotherapy Protocols Biomarkers Tumor Internal Medicine medicine Humans Neoplasm Invasiveness Peritoneal Neoplasms Aged Neoplasm Staging Ovarian Neoplasms Laparotomy biology business.industry Biopsy Needle Wilms' tumor General Medicine medicine.disease Immunohistochemistry Pancreatic Neoplasms medicine.anatomical_structure CA-125 Antigen biology.protein Neoplasms Unknown Primary Female Tomography X-Ray Computed Ovarian cancer Pancreas business Follow-Up Studies Disseminated Carcinoma |
| Zdroj: | Internal Medicine. 43:415-419 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.43.415 |
| Popis: | We report a woman with ascites, hydrothorax, pancreatic tumor, left cystic ovarian tumor, and an elevated serum cancer antigen 125 level. Exploratory laparotomy was performed to determine peritoneal disseminated carcinoma of unknown origin. Immunohistochemical analysis demonstrated positive staining for carcinoembryonic antigen, trypsin, and progesterone receptor and nonspecific or negative reaction for calretinin, estrogen receptor, amylase, lipase, Wilms tumor gene 1 protein, and inhibin or chromogranin A. These results together with the morphology of tubular structure suggested the pathological diagnosis of adenocarcinoma with pancreatic characteristics and contradicted ovarian cancer or mesothelioma. Immunohistochemistry is an adjunct tool to differentiate the primary site of carcinomatous peritonitis. |
| Databáze: | OpenAIRE |
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