Dopaminergic Interplexif orm Cells in the Retina of Pigmented and Hypopigmented Quails (Coturnix coturnix japonica)
| Autor: | Jacques Repérant, Claudine Versaux-Botteri, Jeanine Nguyen-Legros, Najet Dalil-Thiney, Ouria Dkhissi, Evelyne Chanut |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
medicine.medical_specialty
Tyrosine 3-Monooxygenase Dopamine Population Cell Count Coturnix Biology Retina Immunoenzyme Techniques Cellular and Molecular Neuroscience Interneurons Internal medicine biology.animal parasitic diseases medicine Animals cardiovascular diseases education Chromatography High Pressure Liquid education.field_of_study Tyrosine hydroxylase Dopaminergic General Medicine medicine.disease biology.organism_classification Sensory Systems Quail Ophthalmology Endocrinology medicine.anatomical_structure Albinism Coturnix coturnix medicine.drug |
| Zdroj: | Ophthalmic Research. 25:280-288 |
| ISSN: | 1423-0259 0030-3747 |
| DOI: | 10.1159/000267326 |
| Popis: | Interplexiform cells (IPCs) have not been previously described as a component of the population of tyrosine hydroxylase (TH) immunoreactive (presumably dopaminergic) cells in the avian retina. In this study, carried out in both pigmented and imperfect albino mutant quails (Coturnix coturnix japonica), we initially describe TH immunoreactive cells in the inner nuclear layer whose internal dendritic arborization extends into strata 1, 3 and 4/5 of the inner plexiform layer. Then, we describe ascending processes arising from the somata or proximal dendrites of these cells. These sclerally directed processes (100-1,000 microns long) run across the inner nuclear layer to terminate within the outer plexiform layer, sometimes even reaching the outer nuclear layer. Hence, the cells bearing such processes correspond well with the definition of IPCs. The number of scleral processes is higher in mutant (48 +/- 19/retina) than in normal (12 +/- 10/retina) quails and are distributed throughout the retina except the area surrounding the pecten. Comparison of biochemical assays for dopamine in the two strains reveals a significantly higher dopamine content in the mutant quails which could be related to its increased number of dopaminergic IPC processes. |
| Databáze: | OpenAIRE |
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