Treatment for eosinophilic esophagitis
| Autor: | Erin Syverson, Elizabeth J. Hait |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Budesonide
medicine.medical_specialty Allergy Topical Corticosteroid Therapy business.industry Gastroenterology Disease Eosinophilic Esophagitis medicine.disease Dermatology Discontinuation Diet Clinical trial 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis medicine Humans 030211 gastroenterology & hepatology Eosinophilic esophagitis business medicine.drug Fluticasone |
| Zdroj: | Current opinion in gastroenterology. 36(6) |
| ISSN: | 1531-7056 |
| Popis: | Purpose of review To summarize current dietary and pharmacologic approaches in the treatment of eosinophilic esophagitis (EoE). Recent findings Studies comparing dietary approaches in EoE treatment support empiric elimination diets as the preferred approach to dietary EoE treatment, with no data to support use of currently available allergy tests to guide specific food elimination diets. Swallowed topical corticosteroid therapy is the current standard of care in pharmacologic EoE treatment, with similar effectiveness of fluticasone and budesonide, but their discontinuation results in return of both EoE symptoms and disease. A number of nonsteroid-based therapies are currently under investigation for the treatment of EoE, which are focused on targeting disease at a cellular level. Summary EoE can be treated with diet or medications. Empiric elimination is presently the preferred dietary approach. Swallowed steroids is the standard of care to treat EoE with medication; however, there are several promising drugs currently undergoing clinical trials. |
| Databáze: | OpenAIRE |
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