D-dimer as a potential predictor of thromboembolic and cardiovascular complications in patients with chronic kidney disease
| Autor: | O. Ja. Mykhaloiko, I. S. Mykhaloiko, Iryna Dudar, I. Ja. Mykhaloiko |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Ukrainian Biochemical Journal, Vol 92, Iss 3, Pp 71-76 (2020) |
| ISSN: | 2413-5003 2409-4943 |
| Popis: | The aim of the study was to evaluate the relationship between D-dimer levels and different biomarkers of renal diseases to identify the relationship between hypercoagulation and chronic kidney disease (CKD). To achieve this aim, we conducted a one-step prospective observational study involving 140 patients with CKD who were hospitalized in Ivano-Frankivsk Regional Clinical Hospital in Ukraine during 2018-2019. Of these patients, 100 patients (71.4%; 95% CI 53.4-76.7) had glomerulonephritis (GN) and 40 patients (28,6%; 95% CI 21.3-36.8) had diabetic nephropathy (DN). All patients underwent standard examination, which included general clinical, biochemical and instrumental research methods. D-dimer was quantitatively determined in blood serum by enzyme-linked immunosorbent assay (ELISA). The 140 patients were divided into two groups according to the level of D-dimers: normal level ( |
| Databáze: | OpenAIRE |
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