Optimal time to intervene: The case of measles child immunization

Autor: Zuzana Chladná
Rok vydání: 2017
Předmět:
Time Factors
01 natural sciences
Disease Outbreaks
0302 clinical medicine
Germany
Medicine
030212 general & internal medicine
Infectious Disease Medicine
education.field_of_study
Schools
Health Policy
Applied Mathematics
Vaccination
General Medicine
Time optimal
Europe
Computational Mathematics
Child
Preschool

Modeling and Simulation
Vaccination coverage
Medical emergency
General Agricultural and Biological Sciences
Slovakia
Decision Making
Population
World Health Organization
Measles
03 medical and health sciences
Intervention (counseling)
Environmental health
Humans
Computer Simulation
0101 mathematics
education
Health policy
Stochastic Processes
Immunization Programs
business.industry
010102 general mathematics
Infant
Newborn

Infant
Models
Theoretical

medicine.disease
United States
Immunization
Communicable Disease Control
business
Zdroj: Mathematical Biosciences and Engineering. 15:323-335
ISSN: 1551-0018
DOI: 10.3934/mbe.2018014
Popis: The recent measles outbreaks in US and Germany emphasize the importance of sustaining and increasing vaccination rates. In Slovakia, despite mandatory vaccination scheme, decrease in the vaccination rates against measles has been observed in recent years. Different kinds of intervention at the state level, like a law making vaccination a requirement for school entry or education and advertising seem to be the only strategies to improve vaccination coverage. This study aims to analyze the economic effectiveness of intervention in Slovakia. Using real options techniques we determine the level of vaccination rate at which it is optimal to perform intervention. We represent immunization rate of newborns as a stochastic process and intervention as a one-period jump of this process. Sensitivity analysis shows the importance of early intervention in the population with high initial average vaccination coverage. Furthermore, our numerical results demonstrate that the less certain we are about the future development of the immunization rate of newborns, the more valuable is the option to intervene.
Databáze: OpenAIRE