Iron-Catalyzed Alkyne-Based Multicomponent Synthesis of Pyrimidines under Air

Autor:	Nanda D. Paul, Rakesh Mondal, Gargi Chakraborty, Susmita Sarkar, Amit Kumar Guin
Rok vydání:	2021
Předmět:	chemistry.chemical_classification chemistry Iron catalyzed Organic Chemistry Alkyne Surface modification Combinatorial chemistry Iron catalyst Pincer movement
Zdroj:	The Journal of organic chemistry. 86(19)
ISSN:	1520-6904
Popis:	An iron-catalyzed sustainable, economically affordable, and eco-friendly synthetic protocol for the construction of various trisubstituted pyrimidines is described. A wide range of trisubstituted pyrimidines were prepared using a well-defined, easy to prepare, bench-stable, and phosphine-free iron catalyst featuring a redox-noninnocent tridentate arylazo pincer under comparatively mild aerobic conditions via dehydrogenative functionalization of alcohols with alkynes and amidines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5d1d9fd848ff716966a75dc54a2c43 https://pubmed.ncbi.nlm.nih.gov/34528802 Zobrazit plný text záznamu