The complex interplay between mitochondrial dynamics and cardiac metabolism

Autor:	Beverly A. Rothermel, Joseph A. Hill, Hugo Verdejo, Sergio Lavandero, Valentina Parra, Jovan Kuzmicic, Andrea del Campo, Myriam Iglewski, Christian Pennanen
Rok vydání:	2011
Předmět:	Bioenergetics Physiology Fission Myocardium Cell Cardiac metabolism Cell Biology Mitochondrion Biology Models Biological Article Mitochondria Cell biology medicine.anatomical_structure mitochondrial fusion Organelle medicine Humans Mitochondrial fission Energy Metabolism Signal Transduction
Zdroj:	JOURNAL OF BIOENERGETICS AND BIOMEMBRANES Artículos CONICYT CONICYT Chile instacron:CONICYT
ISSN:	1573-6881 0145-479X
DOI:	10.1007/s10863-011-9332-0
Popis:	Mitochondria are highly dynamic organelles, capable of undergoing constant fission and fusion events, forming networks. These dynamic events allow the transmission of chemical and physical messengers and the exchange of metabolites within the cell. In this article we review the signaling mechanisms controlling mitochondrial fission and fusion, and its relationship with cell bioenergetics, especially in the heart. Furthermore we also discuss how defects in mitochondrial dynamics might be involved in the pathogenesis of metabolic cardiac diseases.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3d000537a0060226301bad18c4bea3 https://doi.org/10.1007/s10863-011-9332-0 Zobrazit plný text záznamu Full text from SpringerLink