Isolation of Candida Species is an Important Clue for Suspecting Gastrointestinal Tract Perforation as a Cause of Empyema
| Autor: | Yoshioka Hiroaki, Noboru Takayanagi, Tsutomu Yanagisawa, Toshiko Hoshi, Takashi Ishiguro, Yutaka Sugita, Yoshinori Kawabata, Eishin Hoshi, Tomohiko Ikeya |
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| Rok vydání: | 2010 |
| Předmět: |
Gastric Fistula
Male medicine.medical_specialty Pleural effusion Fistula Perforation (oil well) Candida glabrata Esophageal candidiasis Esophagus Candida albicans Internal Medicine Humans Medicine Lung cancer Empyema Pleural Aged Gastrointestinal tract business.industry General Medicine Middle Aged respiratory system Pleural cavity bacterial infections and mycoses medicine.disease Empyema respiratory tract diseases Surgery body regions surgical procedures operative medicine.anatomical_structure Intestinal Perforation Female business |
| Zdroj: | Internal Medicine. 49:1957-1964 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.49.3667 |
| Popis: | Background Empyema due to Candida species is a rare entity, and the significance of isolation of Candida species from the pleural effusion is not fully understood. Objective To elucidate the clinical features of Candida empyema. Methods We retrospectively reviewed the cases of 128 patients with culture-positive empyema. Results These 128 patients included 7 whose cause of empyema was esophago- or gastropleural fistula. Empyema was due to Candida species in 5 of the 7 patients. Primary diseases of these 5 patients were spontaneous esophageal rupture in 3 patients, esophageal rupture due to lung cancer invasion in 1 patient, and gastric ulcer perforation in 1 patient. None of these 5 patients had esophageal candidiasis. Among the 121 other patients with empyema not due to esophago- or gastropleural fistula, no patient had empyema due to Candida. Conclusion We believe that the empyema in these 5 patients was caused by normal commensal Candida species entering the pleural cavity when the fistula between the gastrointestinal tract and pleural cavity was formed. Isolation of Candida species can be an important clue for suspecting gastrointestinal tract perforation as a cause of empyema. |
| Databáze: | OpenAIRE |
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