Effect of different preparations of hormone therapy on sexual dysfunction in naturally postmenopausal women
Autor: | D Baltaci, T Atasaral, Mehmet A. Osmanagaoglu, Hasan Bozkaya |
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Rok vydání: | 2006 |
Předmět: |
medicine.medical_specialty
Norpregnenes Libido medicine.medical_treatment Sexual arousal Physiology Tibolone law.invention chemistry.chemical_compound Hormone Antagonists Estrogen Receptor Modulators Randomized controlled trial law medicine Humans Nandrolone Single-Blind Method Prospective Studies Gynecology Estradiol business.industry Estrogen Replacement Therapy Coitus Obstetrics and Gynecology General Medicine Middle Aged Postmenopause Sexual Dysfunction Physiological Sexual desire Treatment Outcome Sexual dysfunction Dienogest chemistry Patient Satisfaction Quality of Life Female Hormone therapy medicine.symptom Arousal business medicine.drug |
Zdroj: | Climacteric. 9:464-472 |
ISSN: | 1473-0804 1369-7137 |
DOI: | 10.1080/13697130600997775 |
Popis: | Objective To compare the effect of different formulations of continuous combined hormone therapy on sexual performance in naturally postmenopausal women.Material and methods A total of 158 postmenopausal women were enrolled and prospectively randomized to the single-blind study. Fifty-four women received tibolone 2.5 mg, 53 received 2 mg estradiol and 2 mg dienogest (E2/dienogest), and 51 did not receive any menopausal therapy. The patients were monitored after 6 months. Attitudes of sexuality were evaluated by using the Rosen's female sexual function index.Results Compared with E2/dienogest and the control group, tibolone treatment was associated with more improvement of sexual performance, including sexual desire, sexual arousal and satisfaction. Both of the hormone therapies decreased frequencies of vaginal dryness and painful intercourse.Conclusions Tibolone has more positive effects on the sexual dysfunction of postmenopausal women and may be an alternative to the E2/dienogest preparation in postmeno... |
Databáze: | OpenAIRE |
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