Features of the microelement status in children with acute urticaria

Autor: G. E. Yalovega, A. A. Lebedenko, S. V. Mal’tsev, T. S. Kalmykova, L. A. Averkina, A. N. Posevina, A. O. Funik, O. E. Semernik, V. M. Novikovsky, E. V. Morgul’
Rok vydání: 2016
Předmět:
Zdroj: Pediatričeskaâ Farmakologiâ, Vol 13, Iss 2, Pp 101-104 (2016)
ISSN: 1727-5776
Popis: Background : The increase in the occurrence of allergic dermatoses, especially in young children, is one of the urgent problems of pediatrics. The development of allergic reactions may be caused by changes in microelements balance of the body. Objective : Our aim was to study the features of the microelement status in children with acute urticaria. Methods : A comparative study included patients with acute urticaria of varying severity and healthy children (I and IIA groups of health). Study of microelement was carried out in hair samples by X-ray analysis. Results : The study revealed lower content of zinc in hair in patients with urticaria (n = 40) (48 compared to 146 mcg/g in 23 children of control group, p < 0.001). It also revealed lower content of calcium (447 and 2428 mcg/g respectively; p = 0.001) as well as higher content of sulfur (33860 and 26447 mcg/g respectively; p = 0.001) and potassium (537 and 312 mcg/g respectively; p = 0.001). Differences in the iron, nickel, copper, and chlorine content in hair in comparable groups were not detected. There was no association of microelements content with a burdened hereditary allergologic anamnesis. Conclusion : Children with urticaria have dismicroelemntosis, characterized by a decrease in zinc and calcium content, and an increase in the concentration of sulfur and potassium.
Databáze: OpenAIRE