| Autor: |
Annette T. Byrne, Jochen H.M. Prehn, Livio Trusolino, Claudio Isella, Andrea Bertotti, Diether Lambrechts, Enzo Medico, Rodrigo Dienstmann, Josep Tabernero, Guillem Argilés, Patrick Dicker, Matthias P.A. Ebert, Johannes Betge, Luise Halang, Bram Boeckx, Elodie Modave, Evy Vanderheyden, Manuela Salvucci, Eugenia R. Zanella, Francesco Sassi, Andreas U. Lindner, Niraj Khemka, Giorgia Migliardi, Alice C. O'Farrell, Adam Lafferty |
| Rok vydání: |
2023 |
| Popis: |
Supplementary Figures S1 - S8 and Table S1. Fig S1: Analysis of copy number burden in a PDX population trial of REG treated mCRC PDXs. Fig S2: Effect of REG on microvessel density and proliferation according to CNA cluster. Fig S3 - S6: BCL-2 family profiling of mCRC PDX models via quantitative Western blotting. Fig S7: RPPA protein scores indicating proteins' association with the PDX models' response to REG. Fig S8: Western blot validation of differential EPHA2 protein expression between REG post- and pre-treatment progressor and non-progressor PDX models. Table S1: List of antibodies and dilution factors used against desired targets in RPPA analysis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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