The vestibular evoked myogenic potentials (VEMP) score : a promising tool for evaluation of brainstem involvement in multiple sclerosis
| Autor: | Ivana Zadro, Mario Habek, Barbara Barun, Tereza Gabelić, Ivan Adamec, M. Krbot Skoric |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Multiple Sclerosis Adolescent Vestibular evoked myogenic potential Disease duration Audiology Young Adult Bayesian multivariate linear regression medicine Humans Prospective Studies Expanded Disability Status Scale medicine.diagnostic_test business.industry Multiple sclerosis VEMP score brainstem multiple sclerosis ocular and cervical vestibular evoked myogenic potentials Magnetic resonance imaging medicine.disease Vestibular Evoked Myogenic Potentials Neurology Case-Control Studies Female Neurology (clinical) Brainstem business Brain Stem |
| DOI: | 10.1111/ene.12557 |
| Popis: | Background and purpose Concerning the great importance of brainstem involvement in multiple sclerosis (MS), the aim of this study was to explore the role of the newly developed vestibular evoked myogenic potentials (VEMP) score as a possible marker of brainstem involvement in MS patients. Patients and methods This was a prospective case−control study which included 100 MS patients divided into two groups (without and with clinical signs of brainstem involvement) and 50 healthy controls. Ocular VEMP (oVEMP) and cervical VEMP (cVEMP) measurements were performed in all participants and analyzed for latencies, conduction block and amplitude asymmetry ratio. Based on this the VEMP score was calculated and compared with Expanded Disability Status Scale (EDSS), disease duration and magnetic resonance imaging data. Results Multiple sclerosis patients with clinical signs of brainstem involvement (group 2) had a statistically significant higher percentage of VEMP conduction blocks compared with patients without clinical signs of brainstem involvement (group 1) and healthy controls (P = 0.027 and P |
| Databáze: | OpenAIRE |
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